Generic name: Crisaborole Brand name: Crisle (by Horizon Pharmaceuticals) Strength: 2% ointment Pack size: 10g tube Category: Dermatology → Eczema Care Mechanism of Action Crisaborole is a topical phosphodiesterase‑4 (PDE‑4) inhibitor. It works by reducing inflammatory cytokines in the skin. Provides relief from itching and redness without steroids. Clinical Uses Atopic dermatitis → effective for mild to moderate eczema in adults and children. Helps improve skin barrier function and reduce flare‑ups. Side Effects Common: Mild burning or stinging at application site. Rare: Allergic skin reactions. Precautions: For external use only; avoid eyes and mucous membranes. Patient Counselling Points Apply a thin layer twice daily to affected areas. Wash hands before and after application. Improvement may take several weeks; continue as prescribed. Store below 30°C, away from sunlight and moisture. Keep out of reach of children.